ENZYME entry: EC 1.14.14.42

Accepted Name

homomethionine N-monooxygenase

Alternative Name(s)

CYP79F1

Reaction catalysed

an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]

Comment(s)

Involved in methionine-derived aliphatic glucosinolates biosynthesis.
It catalyzes two successive N-hydroxylations, which are followed by dehydration and decarboxylation.
CYP79F1 from Arabidopsis thaliana can metabolize homo-, di-, tri-, tetra-, penta-, and hexahomomethionine to their corresponding aldoximes, while CYP79F2 from the same plant can only metabolize penta- and hexahomomethionine.
Formerly EC 1.14.13.n5.

Cross-references

BRENDA

1.14.14.42

EC2PDB

1.14.14.42

ExplorEnz

1.14.14.42

PRIAM enzyme-specific profiles

1.14.14.42

KEGG Ligand Database for Enzyme Nomenclature

1.14.14.42

IUBMB Enzyme Nomenclature

1.14.14.42

IntEnz

1.14.14.42

MEDLINE

Find literature relating to 1.14.14.42

MetaCyc

1.14.14.42

Rhea expert-curated reactions

1.14.14.42

UniProtKB/Swiss-Prot

Q949U1, C79F1_ARATH

Q9FUY7, C79F2_ARATH

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