ENZYME entry: EC 1.14.14.42
Accepted Name |
Homomethionine N-monooxygenase.
|
Alternative Name(s) |
CYP79F1. |
Reaction catalysed |
An L-polyhomomethionine + 2 O(2) + 2 [reduced NADPH--hemoprotein reductase] <=> an omega-(methylthio)-(E)-alkanal oxime + CO(2) + 3 H(2)O + 2 [oxidized NADPH--hemoprotein reductase] |
Cofactor(s) |
Heme-thiolate.
|
Comment(s) |
- Involved in methionine-derived aliphatic glucosinolates biosynthesis.
- It catalyzes two successive N-hydroxylations, which are followed by
dehydration and decarboxylation.
- CYP79F1 from Arabidopsis thaliana can metabolize homo-, di-, tri-,
tetra-, penta-, and hexahomomethionine to their corresponding
aldoximes, while CYP79F2 from the same plant can only metabolize
penta- and hexahomomethionine.
- Formerly EC 1.14.13.n5 and EC 1.14.13.n6.
|
Cross-references |
BRENDA | 1.14.14.42 |
EC2PDB | 1.14.14.42 |
ExplorEnz | 1.14.14.42 |
PRIAM enzyme-specific profiles | 1.14.14.42 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.42 |
IUBMB Enzyme Nomenclature | 1.14.14.42 |
IntEnz | 1.14.14.42 |
MEDLINE | Find literature relating to 1.14.14.42 |
MetaCyc | 1.14.14.42 |
Rhea expert-curated reactions | 1.14.14.42 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-