ENZYME entry: EC 1.14.14.42
| Accepted Name |
|---|
| Homomethionine N-monooxygenase.
|
| Alternative Name(s) |
|---|
| CYP79F1. |
| Reaction catalysed |
|---|
| An L-polyhomomethionine + 2 O(2) + 2 [reduced NADPH--hemoprotein reductase] <=> an omega-(methylthio)-(E)-alkanal oxime + CO(2) + 3 H(2)O + 2 [oxidized NADPH--hemoprotein reductase] |
| Cofactor(s) |
|---|
| Heme-thiolate.
|
| Comment(s) |
|---|
- Involved in methionine-derived aliphatic glucosinolates biosynthesis.
- It catalyzes two successive N-hydroxylations, which are followed by
dehydration and decarboxylation.
- CYP79F1 from Arabidopsis thaliana can metabolize homo-, di-, tri-,
tetra-, penta-, and hexahomomethionine to their corresponding
aldoximes, while CYP79F2 from the same plant can only metabolize
penta- and hexahomomethionine.
- Formerly EC 1.14.13.n5 and EC 1.14.13.n6.
|
| Cross-references |
|---|
| BRENDA | 1.14.14.42 |
| EC2PDB | 1.14.14.42 |
| ExplorEnz | 1.14.14.42 |
| PRIAM enzyme-specific profiles | 1.14.14.42 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.42 |
| IUBMB Enzyme Nomenclature | 1.14.14.42 |
| IntEnz | 1.14.14.42 |
| MEDLINE | Find literature relating to 1.14.14.42 |
| MetaCyc | 1.14.14.42 |
| Rhea expert-curated reactions | 1.14.14.42 |
| UniProtKB/Swiss-Prot |
|
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