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ENZYME

ENZYME entry: EC 1.14.14.53

Accepted Name
(R)-limonene 6-monooxygenase
Alternative Name(s)
(+)-limonene-6-hydroxylase
(+)-limonene 6-monooxygenase
Reaction catalysed
(4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] <=> (1R,5S)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • The reaction is stereospecific with over 95% yield of (+)-trans- carveol from (R)-limonene.
  • (S)-Limonene, the substrate for EC 1.14.14.51 is not a substrate.
  • Forms part of the carvone biosynthesis pathway in Carum carvi (caraway) seeds.
  • Formerly EC 1.14.13.80.
Cross-references
BRENDA1.14.14.53
EC2PDB1.14.14.53
ExplorEnz1.14.14.53
PRIAM enzyme-specific profiles1.14.14.53
KEGG Ligand Database for Enzyme Nomenclature1.14.14.53
IUBMB Enzyme Nomenclature1.14.14.53
IntEnz1.14.14.53
MEDLINEFind literature relating to 1.14.14.53
MetaCyc1.14.14.53
Rhea expert-curated reactions1.14.14.53
UniProtKB/Swiss-Prot
P0DO40, CP180_ORIMAP0DO39, CP180_ORIVUP0DO38, CP180_THYVU
P0DO41, CP181_ORIVUP0DO42, CP181_THYVUP11712, CP2C9_HUMAN
P33261, CP2CJ_HUMAN

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