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ENZYME entry: EC 1.14.14.65

Accepted Name
Sugiol synthase.
Alternative Name(s)
CYP76AH3.
Reaction catalysed
Ferruginol + 2 [reduced NADPH--hemoprotein reductase] + 2 O(2) <=> sugiol + 2 [oxidized NADPH--hemoprotein reductase] + 3 H(2)O
Comment(s)
  • Isolated from the plant Salvia miltiorrhiza (danshen).
  • The enzyme also oxidizes 11-hydroxyferruginol to 11-hydroxysugiol.
  • It also oxidizes at C-12 of ferruginol (EC 1.14.14.60).
Cross-references
BRENDA1.14.14.65
EC2PDB1.14.14.65
ExplorEnz1.14.14.65
PRIAM enzyme-specific profiles1.14.14.65
KEGG Ligand Database for Enzyme Nomenclature1.14.14.65
IUBMB Enzyme Nomenclature1.14.14.65
IntEnz1.14.14.65
MEDLINEFind literature relating to 1.14.14.65
MetaCyc1.14.14.65
Rhea expert-curated reactions1.14.14.65
UniProtKB/Swiss-Prot
A0A0Y0GRS3, C76H3_SALMI

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