ENZYME

ENZYME entry: EC 1.14.19.34

Accepted Name

Acyl-lipid (9+3)-(E)-desaturase.

Alternative Name(s)

Acyl-lipid 12-(E)-desaturase.

Reaction catalysed

An oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O(2) + 2 H(+) <=> a (9Z,12E)-octadeca-9,12-dienoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H(2)O
A palmitoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O(2) + 2 H(+) <=> a (9Z,12E)-hexadeca-9,12-dienoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H(2)O

Comment(s)

The enzymes from the plants Dimorphotheca sinuata (African daisy) and Vernicia fordii (tung oil tree) insert a trans double bond in position C-12 of oleate and palmitoleate incorporated into glycerolipids.
The enzyme introduces the new double bond at a position three carbons away from an existing double bond at position 9, toward the methyl end of the fatty acid.
The enzyme from tung oil tree also possesses the activity of EC 1.14.19.33.

Cross-references

BRENDA

EC2PDB

ExplorEnz

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature

IUBMB Enzyme Nomenclature