Home  |  Contact

ENZYME entry: EC 1.14.19.40

Accepted Name
Hex-5-enoyl-[acyl-carrier protein] acetylenase.
Reaction catalysed
Hex-5-enoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O(2) + 2 H(+) <=> hex-5-ynoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H(2)O
Comment(s)
  • The enzyme, characterized from the marine cyanobacterium Moorea producens, is involved in production of the ion channel blocker jamaicamide A.
  • It is specific for hexanoate or hex-5-enoate loaded onto a dedicated acyl-carrier protein (JamC), which is encoded by a gene in the same operon.
Cross-references
BRENDA1.14.19.40
EC2PDB1.14.19.40
ExplorEnz1.14.19.40
PRIAM enzyme-specific profiles1.14.19.40
KEGG Ligand Database for Enzyme Nomenclature1.14.19.40
IUBMB Enzyme Nomenclature1.14.19.40
IntEnz1.14.19.40
MEDLINEFind literature relating to 1.14.19.40
MetaCyc1.14.19.40
Rhea expert-curated reactions1.14.19.40

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-