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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.14.20.14

Accepted Name
Hapalindole-type alkaloid chlorinase.
Reaction catalysed
  • Hapalindole U + 2-oxoglutarate + O(2) + chloride <=> hapalindole G + succinate + CO(2) + H(2)O
  • 12-epi-fischerindole U + 2-oxoglutarate + O(2) + chloride <=> 12-epi-fischerindole G + succinate + CO(2) + H(2)O
Comment(s)
The enzyme, characterized from hapalindole-type alkaloids-producing cyanobacteria, is a specialized iron(II)/2-oxoglutarate-dependent oxygenase that catalyzes the chlorination of its substrates in a reaction that requires oxygen, chloride ions, ferrous iron and 2-oxoglutarate.
Cross-references
BRENDA1.14.20.14
EC2PDB1.14.20.14
ExplorEnz1.14.20.14
PRIAM enzyme-specific profiles1.14.20.14
KEGG Ligand Database for Enzyme Nomenclature1.14.20.14
IUBMB Enzyme Nomenclature1.14.20.14
IntEnz1.14.20.14
MEDLINEFind literature relating to 1.14.20.14
MetaCyc1.14.20.14

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.20.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-