ENZYME entry: EC 1.14.21.4
| Accepted Name |
|---|
| Salutaridine synthase.
|
| Alternative Name(s) |
|---|
| (R)-reticuline oxidase (C-C phenol-coupling). |
| Reaction catalysed |
|---|
| (R)-reticuline + NADPH + O(2) <=> salutaridine + NADP(+) + 2 H(2)O |
| Cofactor(s) |
|---|
| Heme-thiolate.
|
| Comment(s) |
|---|
- Forms the morphinan alkaloid salutaridine by intramolecular phenol
oxidation of reticuline without the incorporation of oxygen into the
product.
- Formerly EC 1.1.3.35.
|
| Cross-references |
|---|
| PROSITE | PDOC00081 |
| BRENDA | 1.14.21.4 |
| EC2PDB | 1.14.21.4 |
| ExplorEnz | 1.14.21.4 |
| PRIAM enzyme-specific profiles | 1.14.21.4 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.21.4 |
| IUBMB Enzyme Nomenclature | 1.14.21.4 |
| IntEnz | 1.14.21.4 |
| MEDLINE | Find literature relating to 1.14.21.4 |
| MetaCyc | 1.14.21.4 |
| UniProtKB/Swiss-Prot |
|
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