Home  |  Contact

ENZYME entry: EC 1.14.99.58

Accepted Name
Heme oxygenase (biliverdin-IX-beta and delta-forming).
Reaction catalysed
  • Protoheme + 3 reduced acceptor + 3 O(2) <=> biliverdin-IX-delta + CO + Fe(2+) + 3 acceptor + 3 H(2)O
  • Protoheme + 3 reduced acceptor + 3 O(2) <=> biliverdin-IX-beta + CO + Fe(2+) + 3 acceptor + 3 H(2)O
Comment(s)
  • The enzyme, characterized from the bacterium Pseudomonas aeruginosa, differs from EC 1.14.15.20 in that the heme substrate is rotated by approximately 110 degrees within the active site, resulting in cleavage at a different part of the ring.
  • It forms a mixture of about 70% biliverdin-IX-delta and 30% biliverdin-IX-beta.
Cross-references
BRENDA1.14.99.58
EC2PDB1.14.99.58
ExplorEnz1.14.99.58
PRIAM enzyme-specific profiles1.14.99.58
KEGG Ligand Database for Enzyme Nomenclature1.14.99.58
IUBMB Enzyme Nomenclature1.14.99.58
IntEnz1.14.99.58
MEDLINEFind literature relating to 1.14.99.58
MetaCyc1.14.99.58
UniProtKB/Swiss-Prot
Q9KL41, HUTZ_VIBCH;  G3XCZ8, PIGA_PSEAE;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-