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ENZYME entry: EC

Accepted Name
heme oxygenase (biliverdin-producing, ferredoxin)
Reaction catalysed
8 H(+) + heme b + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> biliverdin IXalpha + CO + Fe(2+) + 3 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]
  • The enzyme, found in plants, algae, and cyanobacteria, participates in the biosynthesis of phytochromobilin and phytobilins.
  • The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules.
  • The third oxygen molecule provides the oxygen atom that converts the alpha-carbon to CO.
  • Unlike this enzyme, which uses ferredoxin as its electron donor, the electron source for the related mammalian enzyme (EC is EC
PRIAM enzyme-specific profiles1.14.15.20
KEGG Ligand Database for Enzyme Nomenclature1.14.15.20
IUBMB Enzyme Nomenclature1.14.15.20
MEDLINEFind literature relating to
Rhea expert-curated reactions1.14.15.20

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.15.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
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