Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am CEST
. Apologies for the inconvenience.
ENZYME entry: EC 18.104.22.168
View entry in original ENZYME format
View entry in raw text format (no links)
|copper efflux oxidase.|
|4 Cu(+) + 4 H(+) + O2 <=> 4 Cu(2+) + 2 H2O|
- The enzyme, characterized from the bacterium Escherichia coli,
is involved in copper tolerance under aerobic conditions.
- The enzyme contains a substrate binding (type 1) copper site and a
trinuclear copper center (consisting of type 2 and type 3 copper
sites) in which oxygen binding and reduction takes place.
- It also contains a methionine rich region that can bind additional
copper ions. In vitro, if the substrate binding site is occupied by
copper(II), the enzyme can function as a laccase-type quinol oxidase.
- However, in vivo this site is occupied by a copper(I) ion and the
enzyme functions as a cuprous oxidase.
|PRIAM enzyme-specific profiles||22.214.171.124|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.199|
|IUBMB Enzyme Nomenclature||188.8.131.52|
|MEDLINE||Find literature relating to 184.108.40.206|
|Rhea expert-curated reactions||220.127.116.11|
entries corresponding to 1.16.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.16.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-