A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 188.8.131.52
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|Nicotinic acid hydroxylase.|
|Nicotinate + H(2)O + NADP(+) <=> 6-hydroxynicotinate + NADPH|
|Fe cation; Flavoprotein.
- The enzyme is capable of acting on a variety of nicotinate analogs to
varying degrees, including pyrazine-2-carboxylate, pyrazine 2,3-
dicarboxylate, trigonelline and 6-methylnicotinate.
- The enzyme from Clostridium barkeri also possesses a catalytically
essential, labile selenium that can be removed by reaction with
- Forms part of the nicotinate-fermentation catabolism pathway in
- Other enzymes involved in this pathway are EC 184.108.40.206, EC 220.127.116.11,
EC 18.104.22.1681, EC 22.214.171.124, EC 126.96.36.199, EC 188.8.131.52 and EC 184.108.40.206.
- Formerly EC 220.127.116.11.
|PRIAM enzyme-specific profiles||18.104.22.168|
|KEGG Ligand Database for Enzyme Nomenclature||22.214.171.124|
|IUBMB Enzyme Nomenclature||126.96.36.199|
|MEDLINE||Find literature relating to 188.8.131.52|
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