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ENZYME entry: EC 1.17.99.4
Accepted Name |
uracil/thymine dehydrogenase.
|
Alternative Name(s) |
uracil dehydrogenase. |
uracil oxidase. |
uracil-thymine oxidase. |
Reaction catalysed |
- A + H2O + uracil <=> AH2 + barbiturate + H(+)
- A + H2O + thymine <=> 5-methylbarbiturate + AH2 + H(+)
|
Comment(s) |
- Forms part of the oxidative pyrimidine-degrading pathway in some
microorganisms, along with EC 3.5.2.1 and EC 3.5.1.95.
- Mammals, plants and other microorganisms utilize the reductive
pathway, comprising EC 1.3.1.1 or EC 1.3.1.2, EC 3.5.2.2 and
EC 3.5.1.6, with the ultimate degradation products being an L-amino
acid, NH3 and CO2.
- Formerly EC 1.1.99.19 and EC 1.2.99.1.
|
Cross-references |
BRENDA | 1.17.99.4 |
EC2PDB | 1.17.99.4 |
ExplorEnz | 1.17.99.4 |
PRIAM enzyme-specific profiles | 1.17.99.4 |
KEGG Ligand Database for Enzyme Nomenclature | 1.17.99.4 |
IUBMB Enzyme Nomenclature | 1.17.99.4 |
IntEnz | 1.17.99.4 |
MEDLINE | Find literature relating to 1.17.99.4 |
MetaCyc | 1.17.99.4 |
Rhea expert-curated reactions | 1.17.99.4 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.17.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.-.-
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