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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Uracil/thymine dehydrogenase.
Alternative Name(s)
Uracil dehydrogenase.
Uracil oxidase.
Uracil-thymine oxidase.
Reaction catalysed
  • Uracil + H(2)O + acceptor <=> barbiturate + reduced acceptor
  • Thymine + H(2)O + acceptor <=> 5-methylbarbiturate + reduced acceptor
  • Forms part of the oxidative pyrimidine-degrading pathway in some microorganisms, along with EC and EC
  • Mammals, plants and other microorganisms utilize the reductive pathway, comprising EC or EC, EC and EC, with the ultimate degradation products being an L-amino acid, NH(3) and CO(2).
  • Formerly EC and EC
PRIAM enzyme-specific profiles1.17.99.4
KEGG Ligand Database for Enzyme Nomenclature1.17.99.4
IUBMB Enzyme Nomenclature1.17.99.4
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-