ENZYME entry: EC 1.2.1.107
| Accepted Name |
|---|
| Glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring).
|
| Reaction catalysed |
|---|
| D-glyceraldehyde 3-phosphate + arsenate + NAD(+) <=> 1-arsono-3-phospho-D-glycerate + NADH |
| Comment(s) |
|---|
- The enzyme, discovered in bacteria, is very similar to EC 1.2.1.12.
- However, the gene encoding it is located in arsenic resistance
islands in the chromosome, next to a gene (arsJ) that encodes a
transporter that removes the product, 1-arsono-3-phosphoglycerate,
from the cell.
- Together the two proteins form an arsenic detoxification system.
|
| Cross-references |
|---|
| BRENDA | 1.2.1.107 |
| EC2PDB | 1.2.1.107 |
| ExplorEnz | 1.2.1.107 |
| PRIAM enzyme-specific profiles | 1.2.1.107 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.2.1.107 |
| IUBMB Enzyme Nomenclature | 1.2.1.107 |
| IntEnz | 1.2.1.107 |
| MEDLINE | Find literature relating to 1.2.1.107 |
| MetaCyc | 1.2.1.107 |
| Rhea expert-curated reactions | 1.2.1.107 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
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