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ENZYME entry: EC 1.2.1.20

Accepted Name
glutarate-semialdehyde dehydrogenase.
Reaction catalysed
5-oxopentanoate + H2O + NADP(+) <=> glutarate + 2 H(+) + NADPH
Comment(s)
  • The enzyme, characterized from multiple Pseudomonas strains, participates in L-lysine degradation.
  • Unlike earlier claims, it prefers NADP(+) to NAD(+).
Cross-references
BRENDA1.2.1.20
EC2PDB1.2.1.20
ExplorEnz1.2.1.20
PRIAM enzyme-specific profiles1.2.1.20
KEGG Ligand Database for Enzyme Nomenclature1.2.1.20
IUBMB Enzyme Nomenclature1.2.1.20
IntEnz1.2.1.20
MEDLINEFind literature relating to 1.2.1.20
MetaCyc1.2.1.20
Rhea expert-curated reactions1.2.1.20

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-