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ENZYME

ENZYME entry: EC 1.2.1.59

Accepted Name
glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating)
Alternative Name(s)
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
triosephosphate dehydrogenase (NAD(P)(+))
triosephosphate dehydrogenase (NAD(P))
Reaction catalysed
  • D-glyceraldehyde 3-phosphate + NADP(+) + phosphate <=> (2R)-3-phospho-glyceroyl phosphate + H(+) + NADPH
  • D-glyceraldehyde 3-phosphate + NAD(+) + phosphate <=> (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH
Comment(s)
NAD(+) and NADP(+) can be used as cofactors with similar efficiency, unlike EC 1.2.1.12 and EC 1.2.1.13, which are NAD(+)- and NADP(+)- dependent, respectively.
Cross-references
BRENDA1.2.1.59
EC2PDB1.2.1.59
ExplorEnz1.2.1.59
PRIAM enzyme-specific profiles1.2.1.59
KEGG Ligand Database for Enzyme Nomenclature1.2.1.59
IUBMB Enzyme Nomenclature1.2.1.59
IntEnz1.2.1.59
MEDLINEFind literature relating to 1.2.1.59
MetaCyc1.2.1.59
Rhea expert-curated reactions1.2.1.59
UniProtKB/Swiss-Prot
P58837, G3P1_METACQ46AH5, G3P1_METBFO34425, G3P2_BACSU
P58838, G3P2_METACQ465K9, G3P2_METBFP58554, G3P2_NOSS1
P80505, G3P2_SYNY3P34917, G3P2_TRIV2O09452, G3PA_GUITH
Q9YFS9, G3P_AERPEO28542, G3P_ARCFUQ5V061, G3P_HALMA
B0R2M2, G3P_HALS3Q9HSS7, G3P_HALSAQ48335, G3P_HALVA
A2BLC6, G3P_HYPBUA6UUN9, G3P_META3A7IB57, G3P_METB6
P19314, G3P_METBRQ12XM4, G3P_METBUP10618, G3P_METFE
P19315, G3P_METFOQ2FNA2, G3P_METHJQ58546, G3P_METJA
P58839, G3P_METKAA4FZL2, G3P_METM5A9A6M9, G3P_METM6
A6VIW4, G3P_METM7Q8PTD3, G3P_METMAA3CYG8, G3P_METMJ
Q6M0E6, G3P_METMPA5ULT9, G3P_METS3A4YHA5, G3P_METS5
Q2NEN0, G3P_METSTO27090, G3P_METTHA6URW1, G3P_METVS
Q3IUT3, G3P_NATPDQ6L125, G3P_PICTOQ9V1P1, G3P_PYRAB
Q8ZWK7, G3P_PYRAEA4WIW2, G3P_PYRARA3MTU1, G3P_PYRCJ
P61879, G3P_PYRFUO59494, G3P_PYRHOA1RV79, G3P_PYRIL
B1YD06, G3P_PYRNVP61880, G3P_PYRWOP39460, G3P_SACS2
Q4J940, G3P_SULACC3N6F0, G3P_SULIAC4KHW5, G3P_SULIK
C3MQN0, G3P_SULILC3MWN0, G3P_SULIMC3NGT6, G3P_SULIN
C3NEV8, G3P_SULIYQ971K2, G3P_SULTOQ9HJ69, G3P_THEAC
Q5JHB5, G3P_THEKOB6YUU0, G3P_THEONC6A312, G3P_THESM
Q97BJ8, G3P_THEVO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-