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ENZYME entry: EC 1.2.3.7

Accepted Name
Indole-3-acetaldehyde oxidase.
Alternative Name(s)
IAA oxidase.
IAAld oxidase.
Indoleacetaldehyde oxidase.
Reaction catalysed
(Indol-3-yl)acetaldehyde + H(2)O + O(2) <=> (indol-3-yl)acetate + H(2)O(2)
Cofactor(s)
FAD; Heme; Mo cation.
Comment(s)
  • Isoform of EC 1.2.3.1.
  • Has a preference for aldehydes having an indole-ring structure as substrate.
  • May play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild- type Arabidopsis thaliana.
  • While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly.
Cross-references
BRENDA1.2.3.7
EC2PDB1.2.3.7
ExplorEnz1.2.3.7
PRIAM enzyme-specific profiles1.2.3.7
KEGG Ligand Database for Enzyme Nomenclature1.2.3.7
IUBMB Enzyme Nomenclature1.2.3.7
IntEnz1.2.3.7
MEDLINEFind literature relating to 1.2.3.7
MetaCyc1.2.3.7
Rhea expert-curated reactions1.2.3.7
UniProtKB/Swiss-Prot
Q7G193, ALDO1_ARATH;  O23887, ALDO1_MAIZE;  Q7G192, ALDO2_ARATH;  
O23888, ALDO2_MAIZE;  Q7G9P4, ALDO3_ARATH;  Q7G191, ALDO4_ARATH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.3.-
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