ENZYME entry: EC 1.2.5.1
Accepted Name |
pyruvate dehydrogenase (quinone).
|
Alternative Name(s) |
pyruvate dehydrogenase. |
pyruvate dehydrogenase (cytochrome). |
pyruvate oxidase. |
Reaction catalysed |
a ubiquinone + H2O + pyruvate <=> a ubiquinol + acetate + CO2 |
Comment(s) |
- This bacterial enzyme is located on the inner surface of the
cytoplasmic membrane and coupled to the respiratory chain via
ubiquinone.
- Does not accept menaquinone.
- Activity is greatly enhanced by lipids.
- Requires thiamine diphosphate.
- The enzyme can also form acetoin.
|
Cross-references |
BRENDA | 1.2.5.1 |
EC2PDB | 1.2.5.1 |
ExplorEnz | 1.2.5.1 |
PRIAM enzyme-specific profiles | 1.2.5.1 |
KEGG Ligand Database for Enzyme Nomenclature | 1.2.5.1 |
IUBMB Enzyme Nomenclature | 1.2.5.1 |
IntEnz | 1.2.5.1 |
MEDLINE | Find literature relating to 1.2.5.1 |
MetaCyc | 1.2.5.1 |
Rhea expert-curated reactions | 1.2.5.1 |
UniProtKB/Swiss-Prot |
|
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