Expasy logo

ENZYME

ENZYME entry: EC 1.21.3.11

PURL: https://purl.expasy.org/enzyme/EC/1.21.3.11
Accepted Name
precondylocarpine acetate synthase
Reaction catalysed
O-acetyl-15alpha-stemmadenine + O2 = precondylocarpine acetate + H2O2
Comment(s)
  • The enzyme, characterized from the plant Catharanthus roseus (Madagascar periwinkle), participates in a pathway that leads to the production of a number of monoterpene alkaloids, as well as the bisindole alkaloids vinblastine and vincristine, which are used as anticancer drugs.
  • The enzyme is similar to berberine bridge enzymes such as EC 1.21.3.3 and requires an FAD cofactor.
Cross-references
BRENDA1.21.3.11
EC2PDB1.21.3.11
ExplorEnz1.21.3.11
KEGG Ligand Database for Enzyme Nomenclature1.21.3.11
IUBMB Enzyme Nomenclature1.21.3.11
MEDLINEFind literature relating to 1.21.3.11
MetaCyc1.21.3.11
Rhea expert-curated reactions1.21.3.11
UniProtKB/Swiss-Prot
A0A2S1XB67, ASO_CATROA0A5B8X6A1, PAS1_TABIBA0A5B8X7E6, PAS2_TABIB
A0A5B8XB28, PAS3_TABIB

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-