ENZYME entry: EC 1.21.99.5
Accepted Name |
Tetrachloroethene reductive dehalogenase.
|
Alternative Name(s) |
Tetrachloroethene reductase. |
Reaction catalysed |
Trichloroethene + chloride + acceptor <=> tetrachloroethene + reduced acceptor |
Cofactor(s) |
Iron-sulfur.
|
Comment(s) |
- This enzyme allows the common pollutant tetrachloroethene to support
bacterial growth and is responsible for disposal of a number of
chlorinated hydrocarbons by this organism.
- The reaction occurs in the reverse direction.
- The enzyme also reduces trichloroethene to dichloroethene.
- Although the physiological reductant is unknown, the supply of
reductant in some organisms is via reduced menaquinone, itself formed
from molecular hydrogen, via EC 1.12.5.1.
- Methylviologen can act as electron donor.
- Formerly EC 1.97.1.8.
|
Cross-references |
BRENDA | 1.21.99.5 |
EC2PDB | 1.21.99.5 |
ExplorEnz | 1.21.99.5 |
PRIAM enzyme-specific profiles | 1.21.99.5 |
KEGG Ligand Database for Enzyme Nomenclature | 1.21.99.5 |
IUBMB Enzyme Nomenclature | 1.21.99.5 |
IntEnz | 1.21.99.5 |
MEDLINE | Find literature relating to 1.21.99.5 |
MetaCyc | 1.21.99.5 |
Rhea expert-curated reactions | 1.21.99.5 |
UniProtKB/Swiss-Prot |
|
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