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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Tetrachloroethene reductive dehalogenase.
Alternative Name(s)
Tetrachloroethene reductase.
Reaction catalysed
Trichloroethene + chloride + acceptor <=> tetrachloroethene + reduced acceptor
  • This enzyme allows the common pollutant tetrachloroethene to support bacterial growth and is responsible for disposal of a number of chlorinated hydrocarbons by this organism.
  • The reaction occurs in the reverse direction.
  • The enzyme also reduces trichloroethene to dichloroethene.
  • Although the physiological reductant is unknown, the supply of reductant in some organisms is via reduced menaquinone, itself formed from molecular hydrogen, via EC
  • Methylviologen can act as electron donor.
  • Formerly EC
PRIAM enzyme-specific profiles1.21.99.5
KEGG Ligand Database for Enzyme Nomenclature1.21.99.5
IUBMB Enzyme Nomenclature1.21.99.5
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.-.-
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