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ENZYME entry: EC 1.3.1.101
Accepted Name |
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H].
|
Alternative Name(s) |
2,3-digeranylgeranylglycerophospholipid reductase. |
DGGGPL reductase. |
digeranylgeranylglycerophospholipid reductase. |
Reaction catalysed |
- 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NADP(+) <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 H(+) + 8 NADPH
- 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NAD(+) <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 H(+) + 8 NADH
|
Comment(s) |
- The enzyme from the archaeon Thermoplasma acidophilum is involved in
the biosynthesis of membrane lipids.
- In vivo the reaction occurs in the reverse direction with the
formation of 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate. cf.
EC 1.3.7.11.
|
Cross-references |
BRENDA | 1.3.1.101 |
EC2PDB | 1.3.1.101 |
ExplorEnz | 1.3.1.101 |
PRIAM enzyme-specific profiles | 1.3.1.101 |
KEGG Ligand Database for Enzyme Nomenclature | 1.3.1.101 |
IUBMB Enzyme Nomenclature | 1.3.1.101 |
IntEnz | 1.3.1.101 |
MEDLINE | Find literature relating to 1.3.1.101 |
MetaCyc | 1.3.1.101 |
Rhea expert-curated reactions | 1.3.1.101 |
UniProtKB/Swiss-Prot |
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ENZYME /
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