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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Sanguinarine reductase.
Reaction catalysed
  • Dihydrosanguinarine + NAD(P)(+) <=> sanguinarine + NAD(P)H
  • Dihydrochelirubine + NAD(P)(+) <=> chelirubine + NAD(P)H
  • The enzyme, purified from the California poppy (Eschscholzia californica), is involved in detoxifying the phytoalexin sanguinarine produced by poppy itself (cf. EC, when it binds to the cell wall of the poppy cell.
  • The reaction with NADPH is up to three times faster than that with NADH at low concentrations (<10 uM) of the dinucleotide.
  • At higher concentrations the reaction with NADPH is inhibited but not that with NADH.
PRIAM enzyme-specific profiles1.3.1.107
KEGG Ligand Database for Enzyme Nomenclature1.3.1.107
IUBMB Enzyme Nomenclature1.3.1.107
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