ENZYME entry: EC 1.3.1.107
Accepted Name |
sanguinarine reductase.
|
Reaction catalysed |
- dihydrosanguinarine + NADP(+) <=> NADPH + sanguinarine
- dihydrosanguinarine + NAD(+) <=> NADH + sanguinarine
- dihydrochelirubine + NAD(+) <=> chelirubine + NADH
- dihydrochelirubine + NADP(+) <=> chelirubine + NADPH
|
Comment(s) |
- The enzyme, purified from the California poppy (Eschscholzia
californica), is involved in detoxifying the phytoalexin sanguinarine
produced by poppy itself (cf. EC 1.5.3.12), when it binds to the cell
wall of the poppy cell.
- The reaction with NADPH is up to three times faster than that with
NADH at low concentrations (<10 uM) of the dinucleotide.
- At higher concentrations the reaction with NADPH is inhibited but not
that with NADH.
|
Cross-references |
BRENDA | 1.3.1.107 |
EC2PDB | 1.3.1.107 |
ExplorEnz | 1.3.1.107 |
PRIAM enzyme-specific profiles | 1.3.1.107 |
KEGG Ligand Database for Enzyme Nomenclature | 1.3.1.107 |
IUBMB Enzyme Nomenclature | 1.3.1.107 |
IntEnz | 1.3.1.107 |
MEDLINE | Find literature relating to 1.3.1.107 |
MetaCyc | 1.3.1.107 |
Rhea expert-curated reactions | 1.3.1.107 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-