Home  |  Contact

ENZYME entry: EC 1.3.1.116

Accepted Name
7-beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase.
Reaction catalysed
7-beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) <=> 7-beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH
Cofactor(s)
FAD; FMN.
Comment(s)
  • The enzyme, characterized from the bacterium Clostridium scindens, participates in the bile acid 7-alpha-dehydroxylation pathway.
  • The enzyme catalyzes the stereo-specific oxidation of its substrate and has no activity with the 7-alpha anomer.
  • Cf. EC 1.3.1.115.
Cross-references
BRENDA1.3.1.116
EC2PDB1.3.1.116
ExplorEnz1.3.1.116
PRIAM enzyme-specific profiles1.3.1.116
KEGG Ligand Database for Enzyme Nomenclature1.3.1.116
IUBMB Enzyme Nomenclature1.3.1.116
IntEnz1.3.1.116
MEDLINEFind literature relating to 1.3.1.116
MetaCyc1.3.1.116
UniProtKB/Swiss-Prot
P32370, BAIH_CLOSV

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-