ENZYME entry: EC 1.3.1.120
| Accepted Name |
|---|
| Cyclohexane-1-carbonyl-CoA reductase (NADP(+)).
|
| Alternative Name(s) |
|---|
| 1-cyclohexenylcarbonyl-CoA reductase. |
| Reaction catalysed |
|---|
| Cyclohexane-1-carbonyl-CoA + NADP(+) <=> cyclohex-1-ene-1-carbonyl-CoA + NADPH |
| Comment(s) |
|---|
- The enzyme, characterized from the bacterium Streptomyces collinus,
is involved in a pathway that transforms shikimate to cyclohexane-1-
carbonyl-CoA by a series of dehydration and double-bond reduction
steps.
- Most of the steps in this process occur with the carboxylic acid
activated as a coenzyme A thioester.
- The enzyme catalyzes three steps in this pathway, also acting on
(3R,4R)-3,4-dihydroxy-3,4-dihydrobenzoyl-CoA and (5S)-5-
hydroxycyclohex-1-ene-1-carbonyl-CoA.
|
| Cross-references |
|---|
| BRENDA | 1.3.1.120 |
| EC2PDB | 1.3.1.120 |
| ExplorEnz | 1.3.1.120 |
| PRIAM enzyme-specific profiles | 1.3.1.120 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.3.1.120 |
| IUBMB Enzyme Nomenclature | 1.3.1.120 |
| IntEnz | 1.3.1.120 |
| MEDLINE | Find literature relating to 1.3.1.120 |
| MetaCyc | 1.3.1.120 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
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