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ENZYME entry: EC

Accepted Name
enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific).
Alternative Name(s)
acyl-ACP dehydrogenase.
enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific).
Reaction catalysed
a 2,3-saturated acyl-[ACP] + NADP(+) <=> a (2E)-enoyl-[ACP] + H(+) + NADPH
  • This enzyme completes each cycle of fatty acid elongation by catalyzing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to an acyl- carrier protein.
  • It is one of the activities of EC
  • The mammalian enzyme is Re-specific with respect to NADP(+) (cf. EC and and EC
PRIAM enzyme-specific profiles1.3.1.39
KEGG Ligand Database for Enzyme Nomenclature1.3.1.39
IUBMB Enzyme Nomenclature1.3.1.39
MEDLINEFind literature relating to
Rhea expert-curated reactions1.3.1.39
P12276, FAS_CHICK;  P49327, FAS_HUMAN;  P19096, FAS_MOUSE;  
P12785, FAS_RAT;  

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