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ENZYME

ENZYME entry: EC 1.3.1.39

Accepted Name
enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
Alternative Name(s)
acyl-ACP dehydrogenase
enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific)
Reaction catalysed
a 2,3-saturated acyl-[ACP] + NADP(+) <=> a (2E)-enoyl-[ACP] + H(+) + NADPH
Comment(s)
  • This enzyme completes each cycle of fatty acid elongation by catalyzing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to an acyl- carrier protein.
  • It is one of the activities of EC 2.3.1.85.
  • The mammalian enzyme is Re-specific with respect to NADP(+) (cf. EC 1.3.1.10 and and EC 1.3.1.104).
Cross-references
BRENDA1.3.1.39
EC2PDB1.3.1.39
ExplorEnz1.3.1.39
PRIAM enzyme-specific profiles1.3.1.39
KEGG Ligand Database for Enzyme Nomenclature1.3.1.39
IUBMB Enzyme Nomenclature1.3.1.39
IntEnz1.3.1.39
MEDLINEFind literature relating to 1.3.1.39
MetaCyc1.3.1.39
Rhea expert-curated reactions1.3.1.39
UniProtKB/Swiss-Prot
Q2FZQ3, FABI_STAA8Q6GI75, FABI_STAARQ71SP7, FAS_BOVIN
P12276, FAS_CHICKP49327, FAS_HUMANP19096, FAS_MOUSE
P12785, FAS_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
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