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ENZYME

ENZYME entry: EC 1.3.4.1

Accepted Name
fumarate reductase (CoM/CoB)
Alternative Name(s)
thiol:fumarate reductase
Reaction catalysed
coenzyme B + coenzyme M + fumarate = coenzyme M-coenzyme B heterodisulfide + succinate
Comment(s)
  • The enzyme, isolated from the archaeon Methanobacterium thermoautotrophicum, is very oxygen sensitive.
  • It cannot use reduced flavins, reduced coenzyme F420, or NAD(P)H as an electron donor.
  • Distinct from EC 1.3.1.6, EC 1.3.5.1 and EC 1.3.5.4.
  • Formerly EC 1.3.98.2.
Cross-references
BRENDA1.3.4.1
EC2PDB1.3.4.1
ExplorEnz1.3.4.1
PRIAM enzyme-specific profiles1.3.4.1
KEGG Ligand Database for Enzyme Nomenclature1.3.4.1
IUBMB Enzyme Nomenclature1.3.4.1
IntEnz1.3.4.1
MEDLINEFind literature relating to 1.3.4.1
MetaCyc1.3.4.1
Rhea expert-curated reactions1.3.4.1
UniProtKB/Swiss-Prot
D9PU00, TFRA_METTMD9PUX5, TFRB_METTM

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