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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NAD(P)H).
Alternative Name(s)
Pyrroline-2-carboxylate reductase.
Reaction catalysed
  • L-pipecolate + NAD(P)(+) <=> 1-piperideine-2-carboxylate + NAD(P)H
  • L-proline + NAD(P)(+) <=> 1-pyrroline-2-carboxylate + NAD(P)H
  • The enzymes, characterized from the bacterium Azospirillum brasilense, is involved in trans-3-hydroxy-L-proline metabolism.
  • In contrast to EC, which is specific for NADPH, this enzyme shows similar activity with NADPH and NADH.
PRIAM enzyme-specific profiles1.5.1.1
KEGG Ligand Database for Enzyme Nomenclature1.5.1.1
IUBMB Enzyme Nomenclature1.5.1.1
MEDLINEFind literature relating to

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-