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ENZYME entry: EC 1.5.1.34

Accepted Name
6,7-dihydropteridine reductase.
Alternative Name(s)
6,7-dihydropteridine:NAD(P)H oxidoreductase.
DHPR.
Dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase.
Dihydropteridine reductase.
Dihydropteridine reductase (NADH).
NAD(P)H(2):6,7-dihydropteridine oxidoreductase.
NADH-dihydropteridine reductase.
NADPH-dihydropteridine reductase.
NADPH-specific dihydropteridine reductase.
Reaction catalysed
A 5,6,7,8-tetrahydropteridine + NAD(P)(+) <=> a 6,7-dihydropteridine + NAD(P)H
Comment(s)
  • The substrate is the quinonoid form of dihydropteridine.
  • Not identical with EC 1.5.1.3.
  • Formerly EC 1.6.99.7 and EC 1.6.99.10.
Cross-references
PROSITEPDOC00060
BRENDA1.5.1.34
EC2PDB1.5.1.34
ExplorEnz1.5.1.34
PRIAM enzyme-specific profiles1.5.1.34
KEGG Ligand Database for Enzyme Nomenclature1.5.1.34
IUBMB Enzyme Nomenclature1.5.1.34
IntEnz1.5.1.34
MEDLINEFind literature relating to 1.5.1.34
MetaCyc1.5.1.34
Rhea expert-curated reactions1.5.1.34
UniProtKB/Swiss-Prot
Q3T0Z7, DHPR_BOVIN;  Q86A17, DHPR_DICDI;  P09417, DHPR_HUMAN;  
Q8BVI4, DHPR_MOUSE;  Q8MJ30, DHPR_PIG;  P11348, DHPR_RAT;  
P38489, NFSB_ECOLI;  

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