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ENZYME

ENZYME entry: EC 1.5.98.3

PURL: https://purl.expasy.org/enzyme/EC/1.5.98.3
Accepted Name
coenzyme F420:methanophenazine dehydrogenase
Alternative Name(s)
F420H2 dehydrogenase
Reaction catalysed
methanophenazine + reduced coenzyme F420-(gamma-L-Glu)(n) = dihydromethanophenazine + oxidized coenzyme F420-(gamma-L-Glu)(n) + H(+)
Comment(s)
  • The enzyme, found in some methanogenic archaea, is responsible for the reoxidation of coenzyme F420, which is reduced during methanogenesis, and for the reduction of methanophenazine to dihydromethanophenazine, which is required by EC 1.8.98.1.
  • The enzyme is membrane-bound, and is coupled to proton translocation across the cytoplasmic membrane, generating a proton motive force that is used for ATP generation.
Cross-references
BRENDA1.5.98.3
EC2PDB1.5.98.3
ExplorEnz1.5.98.3
KEGG Ligand Database for Enzyme Nomenclature1.5.98.3
IUBMB Enzyme Nomenclature1.5.98.3
MEDLINEFind literature relating to 1.5.98.3
MetaCyc1.5.98.3
Rhea expert-curated reactions1.5.98.3
UniProtKB/Swiss-Prot
Q8PU58, FPOA_METMAF1SVH7, FPOB_METMAF1SVL1, FPOC_METMA
F1SVE4, FPOD_METMAQ8PZ67, FPOF_METMAQ8TQP1, FPOH_METAC
Q466B1, FPOH_METBFQ8PU59, FPOH_METMAQ8PU60, FPOI_METMA
Q8PU61, FPOJ_METMAF1SVE0, FPOK_METMAF1SVK0, FPOL_METMA
F1SVH9, FPOM_METMAF1SVL2, FPON_METMAF1SVE1, FPOO_METMA

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