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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Coenzyme F420:methanophenazine dehydrogenase.
Alternative Name(s)
F420H(2) dehydrogenase.
Reaction catalysed
Reduced coenzyme F420 + methanophenazine <=> oxidized coenzyme F420 + dihydromethanophenazine
  • The enzyme, found in some methanogenic archaea, is responsible for the reoxidation of coenzyme F420, which is reduced during methanogenesis, and for the reduction of methanophenazine to dihydromethanophenazine, which is required by EC
  • The enzyme is membrane-bound, and is coupled to proton translocation across the cytoplasmic membrane, generating a proton motive force that is used for ATP generation.
PRIAM enzyme-specific profiles1.5.98.3
KEGG Ligand Database for Enzyme Nomenclature1.5.98.3
IUBMB Enzyme Nomenclature1.5.98.3
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.98.-
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