Home  |  Contact
Due to maintenance work, this service will be unavailable Mon Feb 13 between 07:00 and 09:30 - CET. Apologies for the inconvenience.

ENZYME entry: EC 1.8.98.1

Accepted Name
dihydromethanophenazine:CoB--CoM heterodisulfide reductase.
Alternative Name(s)
CoB--CoM heterodisulfide reductase.
heterodisulfide reductase.
Reaction catalysed
coenzyme B + coenzyme M + methanophenazine <=> coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine
Comment(s)
  • This enzyme, found in methanogenic archaea that belong to the Methanosarcinales order, regenerates CoM and CoB after the action of EC 2.8.4.1.
  • It is a membrane-bound enzyme that contains (per heterodimeric unit) two distinct b-type hemes and two [4Fe-4S] clusters. cf. EC 1.8.7.3, EC 1.8.98.5, EC 1.8.98.6 and EC 1.8.98.4.
Cross-references
BRENDA1.8.98.1
EC2PDB1.8.98.1
ExplorEnz1.8.98.1
PRIAM enzyme-specific profiles1.8.98.1
KEGG Ligand Database for Enzyme Nomenclature1.8.98.1
IUBMB Enzyme Nomenclature1.8.98.1
IntEnz1.8.98.1
MEDLINEFind literature relating to 1.8.98.1
MetaCyc1.8.98.1
Rhea expert-curated reactions1.8.98.1
UniProtKB/Swiss-Prot
Q8TSV7, HDRD_METAC;  P96797, HDRD_METBF;  Q8PVW3, HDRD_METMA;  
A0A0E3NEE1, HDRD_METTT;  Q8TSV8, HDRE_METAC;  P96796, HDRE_METBF;  
Q8PVW4, HDRE_METMA;  A0A0E3NFS5, HDRE_METTT;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.98.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-