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ENZYME entry: EC 1.7.1.4

Accepted Name
Nitrite reductase (NAD(P)H).
Alternative Name(s)
Assimilatory nitrite reductase.
NAD(P)H:nitrite oxidoreductase.
NADH-nitrite oxidoreductase.
NADPH-nitrite reductase.
Nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)).
Reaction catalysed
Ammonia + 3 NAD(P)(+) + 2 H(2)O <=> nitrite + 3 NAD(P)H
Cofactor(s)
FAD; Fe cation; Iron-sulfur; Siroheme.
Comment(s)
  • The enzymes from the fungi Neurospora crassa, Emericella nidulans and Candida nitratophila and the bacterium Aliivibrio fischeri can use either NADPH or NADH as electron donor.
  • Cf. EC 1.7.1.15.
  • Formerly EC 1.6.6.4.
Cross-references
BRENDA1.7.1.4
EC2PDB1.7.1.4
ExplorEnz1.7.1.4
PRIAM enzyme-specific profiles1.7.1.4
KEGG Ligand Database for Enzyme Nomenclature1.7.1.4
IUBMB Enzyme Nomenclature1.7.1.4
IntEnz1.7.1.4
MEDLINEFind literature relating to 1.7.1.4
MetaCyc1.7.1.4
UniProtKB/Swiss-Prot
P42435, NASD_BACSU;  P42436, NASE_BACSU;  Q06458, NIRB_KLEOX;  
P22944, NIR_EMENI;  P43504, NIR_LEPMC;  P38681, NIR_NEUCR;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.7.1.-
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