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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.8.1.2

Accepted Name
Assimilatory sulfite reductase (NADPH).
Alternative Name(s)
Sulfite reductase (NADPH).
Reaction catalysed
H(2)S + 3 NADP(+) + 3 H(2)O <=> sulfite + 3 NADPH
Cofactor(s)
FAD; FMN; Iron-sulfur; Siroheme.
Comment(s)
  • The enzyme, which catalyzes the six-electron reduction of sulfite to sulfide, is involved in sulfate assimilation in bacteria and yeast.
  • Different from EC 1.8.99.5, which is involved in prokaryotic sulfur- based energy metabolism.
  • Formerly EC 1.8.99.1.
Cross-references
PROSITEPDOC00314
BRENDA1.8.1.2
EC2PDB1.8.1.2
ExplorEnz1.8.1.2
PRIAM enzyme-specific profiles1.8.1.2
KEGG Ligand Database for Enzyme Nomenclature1.8.1.2
IUBMB Enzyme Nomenclature1.8.1.2
IntEnz1.8.1.2
MEDLINEFind literature relating to 1.8.1.2
MetaCyc1.8.1.2
UniProtKB/Swiss-Prot
B5XV25, CYSI1_KLEP3;  C6DCZ7, CYSI1_PECCP;  B5Y1B5, CYSI2_KLEP3;  
C6DDH3, CYSI2_PECCP;  B7JAM6, CYSI_ACIF2;  B5EQW2, CYSI_ACIF5;  
A3N3D8, CYSI_ACTP2;  B3GZ95, CYSI_ACTP7;  B0BT17, CYSI_ACTPJ;  
Q8VSR0, CYSI_ACTPL;  A6VPZ1, CYSI_ACTSZ;  A0KNL0, CYSI_AERHH;  
Q5E840, CYSI_ALIF1;  B5FGI9, CYSI_ALIFM;  B6ELM5, CYSI_ALISL;  
B4RYS6, CYSI_ALTMD;  B7GJU8, CYSI_ANOFW;  Q9KF75, CYSI_BACHD;  
Q65L57, CYSI_BACLD;  A8FDY3, CYSI_BACP2;  Q5WKE7, CYSI_BACSK;  
O32213, CYSI_BACSU;  A7Z8R5, CYSI_BACVZ;  Q1LTP2, CYSI_BAUCH;  
Q7VQH1, CYSI_BLOFL;  Q493N3, CYSI_BLOPB;  A9IT77, CYSI_BORPD;  
C0Z9X2, CYSI_BREBN;  B8D9K5, CYSI_BUCA5;  P57502, CYSI_BUCAI;  
P0C0B2, CYSI_BUCAP;  B8D7V7, CYSI_BUCAT;  Q1QU16, CYSI_CHRSD;  
A8ANX0, CYSI_CITK8;  Q47UW8, CYSI_COLP3;  A7MJ64, CYSI_CROS8;  
C6CLS0, CYSI_DICC1;  C6CAW9, CYSI_DICP7;  A7ZQK6, CYSI_ECO24;  
B7UHH5, CYSI_ECO27;  B7MKN0, CYSI_ECO45;  B7LEI2, CYSI_ECO55;  
Q8X7U2, CYSI_ECO57;  B5Z3C6, CYSI_ECO5E;  B7NTA0, CYSI_ECO7I;  
B7MYR1, CYSI_ECO81;  B7LXH6, CYSI_ECO8A;  C5W865, CYSI_ECOBD;  
C6UCN7, CYSI_ECOBR;  C4ZZR7, CYSI_ECOBW;  A8A3P4, CYSI_ECOHS;  
A1AEU9, CYSI_ECOK1;  Q0TEA3, CYSI_ECOL5;  Q8FEI8, CYSI_ECOL6;  
B1IU78, CYSI_ECOLC;  P17846, CYSI_ECOLI;  B7N6Z7, CYSI_ECOLU;  
B6I6F7, CYSI_ECOSE;  B1LQ86, CYSI_ECOSM;  Q1R7T5, CYSI_ECOUT;  
A4WDW0, CYSI_ENT38;  B2VG06, CYSI_ERWT9;  B7LWN9, CYSI_ESCF3;  
Q5L041, CYSI_GEOKA;  A4IMT6, CYSI_GEOTN;  A6TD48, CYSI_KLEP7;  
B0SF75, CYSI_LEPBA;  B0SNL6, CYSI_LEPBP;  B1HXC1, CYSI_LYSSC;  
Q65T54, CYSI_MANSM;  B7L0Y4, CYSI_METC4;  C5APZ1, CYSI_METEA;  
A9W4X6, CYSI_METEP;  B8IRY2, CYSI_METNO;  B1Z7C5, CYSI_METPB;  
B1LS97, CYSI_METRJ;  B0U8Y9, CYSI_METS4;  B8EKI5, CYSI_METSB;  
Q1D9W9, CYSI_MYXXD;  A9LZ72, CYSI_NEIM0;  Q9JUD9, CYSI_NEIMA;  
Q9JS33, CYSI_NEIMB;  A1KU05, CYSI_NEIMF;  Q0AGU3, CYSI_NITEC;  
Q82W45, CYSI_NITEU;  Q1QQC7, CYSI_NITHX;  Q3JBJ1, CYSI_NITOC;  
Q3SV33, CYSI_NITWN;  Q8EQP0, CYSI_OCEIH;  B6JCW3, CYSI_OLICO;  
C6CXN6, CYSI_PAESJ;  Q6D1A2, CYSI_PECAS;  Q7N8L5, CYSI_PHOLL;  
Q6LM59, CYSI_PHOPR;  B4F234, CYSI_PROMH;  Q15NK1, CYSI_PSEA6;  
Q3IFM1, CYSI_PSEHT;  A1T054, CYSI_PSYIN;  B5F430, CYSI_SALA4;  
A9MF17, CYSI_SALAR;  Q57KH8, CYSI_SALCH;  B5FTU2, CYSI_SALDC;  
B5QW35, CYSI_SALEP;  B5RDS0, CYSI_SALG2;  B4TFY4, CYSI_SALHS;  
B4T474, CYSI_SALNS;  Q5PEH8, CYSI_SALPA;  A9N2E5, CYSI_SALPB;  
C0PXC5, CYSI_SALPC;  B5BEZ8, CYSI_SALPK;  B4TTX8, CYSI_SALSV;  
Q8Z459, CYSI_SALTI;  P17845, CYSI_SALTY;  A8G9X7, CYSI_SERP5;  
A1S9I4, CYSI_SHEAM;  B8EE51, CYSI_SHEB2;  A3D829, CYSI_SHEB5;  
A6WJT5, CYSI_SHEB8;  A9L2P8, CYSI_SHEB9;  Q12QQ5, CYSI_SHEDO;  
Q07Y86, CYSI_SHEFN;  B0TTE4, CYSI_SHEHH;  A3QAP0, CYSI_SHELP;  
Q8EB00, CYSI_SHEON;  A8H094, CYSI_SHEPA;  A4Y9Z3, CYSI_SHEPC;  
B8CJV9, CYSI_SHEPW;  A0KTH5, CYSI_SHESA;  A8FZY7, CYSI_SHESH;  
Q0HFL7, CYSI_SHESM;  Q0HYB3, CYSI_SHESR;  A1RGD7, CYSI_SHESW;  
B1KE86, CYSI_SHEWM;  B2TZH1, CYSI_SHIB3;  Q31XM5, CYSI_SHIBS;  
Q32CG4, CYSI_SHIDS;  Q0T1I7, CYSI_SHIF8;  Q83QE0, CYSI_SHIFL;  
Q3YY95, CYSI_SHISS;  Q2NVN3, CYSI_SODGM;  B9DLM4, CYSI_STACT;  
Q5HKZ7, CYSI_STAEQ;  Q8CMX5, CYSI_STAES;  Q4L9F1, CYSI_STAHJ;  
Q49UL9, CYSI_STAS1;  P52673, CYSI_THIRO;  C4L9J8, CYSI_TOLAT;  
A5F3I5, CYSI_VIBC3;  A7MSZ7, CYSI_VIBCB;  Q9KUX3, CYSI_VIBCH;  
C3LRB7, CYSI_VIBCM;  Q87L91, CYSI_VIBPA;  B7VI85, CYSI_VIBTL;  
Q8DCK1, CYSI_VIBVU;  Q7MHA6, CYSI_VIBVY;  Q8PHC8, CYSI_XANAC;  
Q3BPY4, CYSI_XANC5;  Q4UY08, CYSI_XANC8;  B0RPG6, CYSI_XANCB;  
Q8P608, CYSI_XANCP;  Q2P0H2, CYSI_XANOM;  B2SI05, CYSI_XANOP;  
Q8KQT8, CYSI_XANOR;  B2IA31, CYSI_XYLF2;  Q9PD81, CYSI_XYLFA;  
B0U6W0, CYSI_XYLFM;  Q87DH0, CYSI_XYLFT;  A1JJS3, CYSI_YERE8;  
A7FLY9, CYSI_YERP3;  Q1C3Z1, CYSI_YERPA;  B2K566, CYSI_YERPB;  
Q8ZBN7, CYSI_YERPE;  Q1CLS7, CYSI_YERPN;  A4TPY6, CYSI_YERPP;  
Q66ED3, CYSI_YERPS;  B1JK04, CYSI_YERPY;  Q5NRM2, CYSI_ZYMMO;  
Q5E841, CYSJ_ALIF1;  O32214, CYSJ_BACSU;  Q1LTP1, CYSJ_BAUCH;  
Q7VQH2, CYSJ_BLOFL;  P57503, CYSJ_BUCAI;  Q8K9D3, CYSJ_BUCAP;  
A8ANX1, CYSJ_CITK8;  A7MJ63, CYSJ_CROS8;  A7ZQK7, CYSJ_ECO24;  
Q8X7U1, CYSJ_ECO57;  A8A3P5, CYSJ_ECOHS;  A1AEV0, CYSJ_ECOK1;  
Q0TEA2, CYSJ_ECOL5;  Q8FEI7, CYSJ_ECOL6;  B1IU77, CYSJ_ECOLC;  
P38038, CYSJ_ECOLI;  Q1R7T4, CYSJ_ECOUT;  A4WDW1, CYSJ_ENT38;  
A6TD49, CYSJ_KLEP7;  Q65T53, CYSJ_MANSM;  A9LZ73, CYSJ_NEIM0;  
Q9JUD8, CYSJ_NEIMA;  Q9JS45, CYSJ_NEIMB;  A1KU06, CYSJ_NEIMF;  
Q6D1A1, CYSJ_PECAS;  Q7N8L6, CYSJ_PHOLL;  Q6LM58, CYSJ_PHOPR;  
A9MF16, CYSJ_SALAR;  Q57KH7, CYSJ_SALCH;  Q5PEH7, CYSJ_SALPA;  
A9N2E6, CYSJ_SALPB;  Q8Z458, CYSJ_SALTI;  P38039, CYSJ_SALTY;  
A8G9X6, CYSJ_SERP5;  Q8EAZ9, CYSJ_SHEON;  A0KTH4, CYSJ_SHESA;  
Q0HFL6, CYSJ_SHESM;  Q0HYB4, CYSJ_SHESR;  Q31XM4, CYSJ_SHIBS;  
Q32CG3, CYSJ_SHIDS;  Q0T1I8, CYSJ_SHIF8;  Q83QD9, CYSJ_SHIFL;  
Q3YY94, CYSJ_SHISS;  Q2NVN4, CYSJ_SODGM;  P52674, CYSJ_THIRO;  
A5F3I4, CYSJ_VIBC3;  Q9KUX4, CYSJ_VIBCH;  Q87L90, CYSJ_VIBPA;  
Q8DCK2, CYSJ_VIBVU;  Q7MHA5, CYSJ_VIBVY;  A1JJS2, CYSJ_YERE8;  
A7FLZ0, CYSJ_YERP3;  Q1C3Z0, CYSJ_YERPA;  Q8ZBN6, CYSJ_YERPE;  
Q1CLS8, CYSJ_YERPN;  A4TPY5, CYSJ_YERPP;  Q66ED4, CYSJ_YERPS;  
Q5NRM1, CYSJ_ZYMMO;  Q09878, MET10_SCHPO;  P39692, MET10_YEAST;  
Q1K9C2, MET5_SCHPO;  P47169, MET5_YEAST;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-