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ENZYME

ENZYME entry: EC 1.8.4.16

Accepted Name
thioredoxin:protein disulfide reductase
Reaction catalysed
[protein]-dithiol + [thioredoxin]-disulfide <=> [protein]-disulfide + [thioredoxin]-dithiol
Comment(s)
  • The DsbD protein is found in Gram-negative bacteria and transfers electrons from cytoplasmic thioredoxin to the periplasmic substrate proteins DsbC, DsbG and CcmG, reducing disulfide bonds in the target proteins to dithiols.
  • NrdH redoxins, which are found in Gram-positive bacteria, catalyze a similar reaction.
Cross-references
BRENDA1.8.4.16
EC2PDB1.8.4.16
ExplorEnz1.8.4.16
PRIAM enzyme-specific profiles1.8.4.16
KEGG Ligand Database for Enzyme Nomenclature1.8.4.16
IUBMB Enzyme Nomenclature1.8.4.16
IntEnz1.8.4.16
MEDLINEFind literature relating to 1.8.4.16
MetaCyc1.8.4.16
Rhea expert-curated reactions1.8.4.16

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-