ENZYME

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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.8.4.7

Accepted Name
Enzyme-thiol transhydrogenase (glutathione-disulfide).
Alternative Name(s)
[Xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase.
Enzyme-thiol transhydrogenase (oxidized-glutathione).
Glutathione-dependent thiol:disulfide oxidoreductase.
Thiol:disulfide oxidoreductase.
Reaction catalysed
[Xanthine dehydrogenase] + glutathione disulfide <=> [xanthine oxidase] + 2 glutathione
Comment(s)
Converts EC 1.17.1.4 into EC 1.17.3.2 in the presence of glutathione disulfide. Also reduces the disulfide bond of ricin. Not inhibited by Cu(2+) or thiol reagents.
Cross-references
BRENDA	1.8.4.7
EC2PDB	1.8.4.7
ExplorEnz	1.8.4.7
PRIAM enzyme-specific profiles	1.8.4.7
KEGG Ligand Database for Enzyme Nomenclature	1.8.4.7
IUBMB Enzyme Nomenclature	1.8.4.7
IntEnz	1.8.4.7
MEDLINE	Find literature relating to 1.8.4.7
MetaCyc	1.8.4.7

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