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ENZYME

ENZYME entry: EC 1.8.4.7

PURL: https://purl.expasy.org/enzyme/EC/1.8.4.7
Accepted Name
enzyme-thiol transhydrogenase (glutathione-disulfide)
Alternative Name(s)
[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase
enzyme-thiol transhydrogenase (oxidized-glutathione)
glutathione-dependent thiol:disulfide oxidoreductase
thiol:disulfide oxidoreductase
Reaction catalysed
[xanthine dehydrogenase] + glutathione disulfide = [xanthine oxidase] + 2 glutathione
Comment(s)
  • Converts EC 1.17.1.4 into EC 1.17.3.2 in the presence of glutathione disulfide.
  • Also reduces the disulfide bond of ricin.
  • Not inhibited by Cu(2+) or thiol reagents.
Cross-references
BRENDA1.8.4.7
EC2PDB1.8.4.7
ExplorEnz1.8.4.7
KEGG Ligand Database for Enzyme Nomenclature1.8.4.7
IUBMB Enzyme Nomenclature1.8.4.7
MEDLINEFind literature relating to 1.8.4.7
MetaCyc1.8.4.7
Rhea expert-curated reactions1.8.4.7

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-