A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 126.96.36.199
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|Sarcosine dimethylglycine N-methyltransferase.|
|2 S-adenosyl-L-methionine + sarcosine <=> 2 S-adenosyl-L-homocysteine + betaine|
- Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece
halophytica synthesize betaine from glycine by a three-step
- The first enzyme, EC 188.8.131.52, leads to the formation of either
sarcosine or N,N-dimethylglycine, which is further methylated to
yield betaine (N,N,N-trimethylglycine) by the action of this enzyme.
- Both of these enzymes can catalyze the formation of
N,N-dimethylglycine from sarcosine.
- The reactions are strongly inhibited by S-adenosyl-L-homocysteine.
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
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