A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 188.8.131.52
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|Glycine sarcosine N-methyltransferase.|
|2 S-adenosyl-L-methionine + glycine <=> 2 S-adenosyl-L-homocysteine + N,N-dimethylglycine|
- Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece
halophytica synthesize betaine from glycine by a three-step
- This is the first enzyme and it leads to the formation of either
sarcosine or N,N-dimethylglycine, which is further methylated to
yield betaine (N,N,N-trimethylglycine) by the action of EC 184.108.40.206.
- Differs from EC 220.127.116.11, as it can further methylate the product of
the first reaction.
- Acetate, dimethylglycine and S-adenosyl-L-homocysteine can inhibit
|PRIAM enzyme-specific profiles||18.104.22.168|
|KEGG Ligand Database for Enzyme Nomenclature||22.214.171.124|
|IUBMB Enzyme Nomenclature||126.96.36.199|
|MEDLINE||Find literature relating to 188.8.131.52|
entries corresponding to 2.1.1.-
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