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ENZYME

ENZYME entry: EC 2.1.1.161

Accepted Name
dimethylglycine N-methyltransferase
Alternative Name(s)
DMT
Reaction catalysed
N,N-dimethylglycine + S-adenosyl-L-methionine <=> glycine betaine + H(+) + S-adenosyl-L-homocysteine
Comment(s)
  • This enzyme, from the marine cyanobacterium Synechococcus sp. strain WH8102, differs from EC 2.1.1.157 in that it cannot use sarcosine as an alternative substrate.
  • Betaine is a 'compatible solute' that enables cyanobacteria to cope with osmotic stress by maintaining a positive cellular turgor.
Cross-references
BRENDA2.1.1.161
EC2PDB2.1.1.161
ExplorEnz2.1.1.161
PRIAM enzyme-specific profiles2.1.1.161
KEGG Ligand Database for Enzyme Nomenclature2.1.1.161
IUBMB Enzyme Nomenclature2.1.1.161
IntEnz2.1.1.161
MEDLINEFind literature relating to 2.1.1.161
MetaCyc2.1.1.161
Rhea expert-curated reactions2.1.1.161
UniProtKB/Swiss-Prot
Q7U4Z9, SDMT_PARMW

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