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ENZYME

ENZYME entry: EC 2.1.1.195

Accepted Name
cobalt-precorrin-5B (C(1))-methyltransferase
Alternative Name(s)
cobalt-precorrin-6A synthase
Reaction catalysed
Co-precorrin-5B + S-adenosyl-L-methionine <=> Co-precorrin-6A + S-adenosyl-L-homocysteine
Comment(s)
  • This enzyme catalyzes the C-1 methylation of cobalt-precorrin-5B in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis.
  • See EC 2.1.1.152 for the C-1 methyltransferase that participates in the aerobic cobalamin biosynthesis pathway.
Cross-references
BRENDA2.1.1.195
EC2PDB2.1.1.195
ExplorEnz2.1.1.195
PRIAM enzyme-specific profiles2.1.1.195
KEGG Ligand Database for Enzyme Nomenclature2.1.1.195
IUBMB Enzyme Nomenclature2.1.1.195
IntEnz2.1.1.195
MEDLINEFind literature relating to 2.1.1.195
MetaCyc2.1.1.195
Rhea expert-curated reactions2.1.1.195
UniProtKB/Swiss-Prot
Q8UBQ6, CBID_AGRFCA6TJE5, CBID_ALKMQA8MG25, CBID_ALKOO
O29535, CBID_ARCFUA5EGH4, CBID_BRASBB2S6D5, CBID_BRUA1
Q2YQL5, CBID_BRUA2A6X049, CBID_BRUA4Q57CK0, CBID_BRUAB
A9M5W0, CBID_BRUC2C0RJR0, CBID_BRUMBQ8YHU3, CBID_BRUME
A5VR64, CBID_BRUO2Q8G018, CBID_BRUSUB1YQE3, CBID_BURA4
A0K7F1, CBID_BURCHB4E9C7, CBID_BURCJQ39GJ4, CBID_BURL3
A9AHY0, CBID_BURM1Q62KC5, CBID_BURMAB1K168, CBID_BURO0
Q1BWA2, CBID_BURO1Q63U59, CBID_BURPSQ2SVY2, CBID_BURTA
A4JEB6, CBID_BURVGQ7NXR0, CBID_CHRVOB5EC81, CBID_CITBB
A8AEP5, CBID_CITK8Q97JA9, CBID_CLOABA7FSI4, CBID_CLOB1
C3L308, CBID_CLOB6A6LVU2, CBID_CLOB8B2UXF7, CBID_CLOBA
B2TPG6, CBID_CLOBBA5I0C8, CBID_CLOBHC1FVD5, CBID_CLOBJ
B1IHE5, CBID_CLOBKA7GBX9, CBID_CLOBLB1KY30, CBID_CLOBM
Q180S8, CBID_CLOD6B9DZM2, CBID_CLOK1A5N646, CBID_CLOK5
A0Q345, CBID_CLONNQ0TR61, CBID_CLOP1Q8XL16, CBID_CLOPE
Q0STJ5, CBID_CLOPSQ897K1, CBID_CLOTEB8HS30, CBID_CYAP4
Q47FE4, CBID_DECARQ24Q31, CBID_DESHYQ6ARS6, CBID_DESPS
C5BFT8, CBID_EDWI9Q8REW8, CBID_FUSNNB9M7V0, CBID_GEODF
Q5KZ00, CBID_GEOKAQ39YF3, CBID_GEOMGP61985, CBID_GEOSL
C6E679, CBID_GEOSMC5DAN8, CBID_GEOSWA4IP00, CBID_GEOTN
Q7NK51, CBID_GLOVIQ2S8B2, CBID_HAHCHA1WYD1, CBID_HALHL
B5XUU2, CBID_KLEP3A6TDC4, CBID_KLEP7Q04NF4, CBID_LEPBJ
Q04WN5, CBID_LEPBLP61986, CBID_LEPICQ8EXP6, CBID_LEPIN
Q92CL4, CBID_LISINC1L299, CBID_LISMCQ720N5, CBID_LISMF
B8DC39, CBID_LISMHQ8Y7S7, CBID_LISMOA0AHT7, CBID_LISW6
A6W0Q2, CBID_MARMSA6UT10, CBID_META3Q8TTB6, CBID_METAC
A7I7N1, CBID_METB6Q46CE4, CBID_METBFQ12VD1, CBID_METBU
Q9X7G7, CBID_METC4Q605I7, CBID_METCAQ2FRR2, CBID_METHJ
Q60342, CBID_METJAQ8TYG5, CBID_METKAA4FWX4, CBID_METM5
A9AAB0, CBID_METM6A6VGE3, CBID_METM7Q8PWA9, CBID_METMA
A3CSU7, CBID_METMJP61988, CBID_METMPA5ULG4, CBID_METS3
Q2NHX5, CBID_METSTO26899, CBID_METTHA6UPK3, CBID_METVS
Q2RJI7, CBID_MOOTAP61984, CBID_NITV2Q8YT79, CBID_NOSS1
A1TI97, CBID_PARC0Q2W3X9, CBID_PARM1Q7UA54, CBID_PARMW
B2JRI2, CBID_PARP8B2TBS5, CBID_PARPJQ13MI0, CBID_PARXL
A1ANJ7, CBID_PELPDQ7N2S8, CBID_PHOLLQ3V8B2, CBID_PICTO
A1VP90, CBID_POLNAQ129V0, CBID_POLSJO87693, CBID_PRIMG
B4S8C4, CBID_PROA2A2BZD8, CBID_PROM1A8G222, CBID_PROM2
A2C5P1, CBID_PROM3A2BTY3, CBID_PROM5Q31DE8, CBID_PROM9
Q7VEH6, CBID_PROMAQ7V9B0, CBID_PROMMQ7V3N8, CBID_PROMP
Q46I27, CBID_PROMTQ48DG3, CBID_PSE14A6V3I3, CBID_PSEA7
B7V6W0, CBID_PSEA8Q02P70, CBID_PSEABQ9HZT9, CBID_PSEAE
Q1I4B1, CBID_PSEE4Q4KIY6, CBID_PSEF5A5W9L9, CBID_PSEP1
Q3KIR0, CBID_PSEPFB0KK08, CBID_PSEPGQ88DJ4, CBID_PSEPK
B1J5X5, CBID_PSEPWQ87VQ6, CBID_PSESMQ4ZN23, CBID_PSEU2
Q8ZZB0, CBID_PYRAEQ8XS59, CBID_RALN1Q8GDE1, CBID_RHORT
Q1AYB7, CBID_RUBXDB8I0Q1, CBID_RUMCHQ97WC6, CBID_SACS2
B5EWZ8, CBID_SALA4A8M4X3, CBID_SALAIA9MLR2, CBID_SALAR
Q57MW5, CBID_SALCHB5FM00, CBID_SALDCB5QYY9, CBID_SALEP
B4T8Y4, CBID_SALHSB4SX00, CBID_SALNSQ5PDT5, CBID_SALPA
A9MT88, CBID_SALPBC0Q1P4, CBID_SALPCB5BG44, CBID_SALPK
B4TZR1, CBID_SALSVQ8Z5M8, CBID_SALTIA4X7W7, CBID_SALTO
Q05628, CBID_SALTYQ4JBL6, CBID_SULACC3N0H9, CBID_SULIA
C4KJM9, CBID_SULIKC3MJI6, CBID_SULILC3MTW9, CBID_SULIM
C3NJQ6, CBID_SULINC3N8G7, CBID_SULIYQ96ZL3, CBID_SULTO
Q3A7A9, CBID_SYNC1Q31RU7, CBID_SYNE7Q2JI70, CBID_SYNJB
Q5N2F9, CBID_SYNP6Q3B0W2, CBID_SYNS9Q3ANK8, CBID_SYNSC
P73423, CBID_SYNY3B7IHG0, CBID_THEABQ9HKE5, CBID_THEAC
B0K2K5, CBID_THEPXP61989, CBID_THET2Q8DKT8, CBID_THEVB
Q97A63, CBID_THEVOC4LFC1, CBID_TOLATP61987, CBID_TREDE
Q3MEA9, CBID_TRIV2C5CPF1, CBID_VARPS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
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