ENZYME entry: EC 2.1.1.196
Accepted Name |
Cobalt-precorrin-6B (C(15))-methyltransferase (decarboxylating).
|
Alternative Name(s) |
Cobalt-precorrin-6Y (C(15))-methyltransferase (decarboxylating). |
Reaction catalysed |
S-adenosyl-L-methionine + cobalt-precorrin-6B <=> S-adenosyl-L-homocysteine + cobalt-precorrin-7 + CO(2) |
Comment(s) |
- This enzyme, which participates in the anaerobic (early cobalt
insertion) adenosylcobalamin biosynthesis pathway, catalyzes both
methylation at C-15 and decarboxylation of the C-12 acetate side
chain of cobalt-precorrin-6B.
- The equivalent activity in the aerobic adenosylcobalamin biosynthesis
pathway is catalyzed by the bifunctional enzyme EC 2.1.1.132.
|
Cross-references |
BRENDA | 2.1.1.196 |
EC2PDB | 2.1.1.196 |
ExplorEnz | 2.1.1.196 |
PRIAM enzyme-specific profiles | 2.1.1.196 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.196 |
IUBMB Enzyme Nomenclature | 2.1.1.196 |
IntEnz | 2.1.1.196 |
MEDLINE | Find literature relating to 2.1.1.196 |
MetaCyc | 2.1.1.196 |
Rhea expert-curated reactions | 2.1.1.196 |
UniProtKB/Swiss-Prot |
O87694, CBIET_PRIMG; | O29526, CBIT_ARCFU; | Q9HPN4, CBIT_HALSA; |
Q8TI93, CBIT_METAC; | Q57836, CBIT_METJA; | A4FWV6, CBIT_METM5; |
A9AA91, CBIT_METM6; | A6VGG1, CBIT_METM7; | Q8PY64, CBIT_METMA; |
P61820, CBIT_METMP; | A5UJR5, CBIT_METS3; | O26249, CBIT_METTH; |
A6UPM1, CBIT_METVS; | Q8ZZA9, CBIT_PYRAE; | A3MWC5, CBIT_PYRCJ; |
Q97WC7, CBIT_SACS2; | Q8Z5M9, CBIT_SALTI; | Q05632, CBIT_SALTY; |
Q4JBL7, CBIT_SULAC; | C3N0H8, CBIT_SULIA; | C4KJM8, CBIT_SULIK; |
C3MJI5, CBIT_SULIL; | C3MTW8, CBIT_SULIM; | C3NJQ5, CBIT_SULIN; |
C3N8G6, CBIT_SULIY; | Q96ZL5, CBIT_SULTO; | Q9HKE4, CBIT_THEAC; |
Q97A64, CBIT_THEVO; |
|
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