ENZYME entry: EC 2.1.1.20
Accepted Name |
glycine N-methyltransferase.
|
Alternative Name(s) |
glycine methyltransferase. |
Reaction catalysed |
glycine + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + sarcosine |
Comment(s) |
- Thought to play an important role in the regulation of methyl group
metabolism in the liver and pancreas by regulating the ratio between
S-adenosyl-L-methionine and S-adenosyl-L-homocysteine.
- Inhibited by 5-methyltetrahydrofolate pentaglutamate.
- Sarcosine, which has no physiological role, is converted back into
glycine by the action of EC 1.5.8.3.
|
Cross-references |
BRENDA | 2.1.1.20 |
EC2PDB | 2.1.1.20 |
ExplorEnz | 2.1.1.20 |
PRIAM enzyme-specific profiles | 2.1.1.20 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.20 |
IUBMB Enzyme Nomenclature | 2.1.1.20 |
IntEnz | 2.1.1.20 |
MEDLINE | Find literature relating to 2.1.1.20 |
MetaCyc | 2.1.1.20 |
Rhea expert-curated reactions | 2.1.1.20 |
UniProtKB/Swiss-Prot |
|
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