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ENZYME

ENZYME entry: EC 2.1.1.216

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.216
Accepted Name
tRNA (guanine(26)-N(2))-dimethyltransferase
Alternative Name(s)
tRNA (m(2)2G26)dimethyltransferase
Reaction catalysed
guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)
Comment(s)
  • The enzyme dissociates from its tRNA substrate between the two consecutive methylation reactions.
  • In contrast to EC 2.1.1.215, this enzyme does not catalyze the methylation of guanine(27) in tRNA.
  • Formerly EC 2.1.1.32.
Cross-references
BRENDA2.1.1.216
EC2PDB2.1.1.216
ExplorEnz2.1.1.216
KEGG Ligand Database for Enzyme Nomenclature2.1.1.216
IUBMB Enzyme Nomenclature2.1.1.216
MEDLINEFind literature relating to 2.1.1.216
MetaCyc2.1.1.216
Rhea expert-curated reactions2.1.1.216
UniProtKB/Swiss-Prot
Q9YDY7, TRM1_AERPEQ9LFU5, TRM1_ARATHO29443, TRM1_ARCFU
Q23270, TRM1_CAEELQ9VK89, TRM1_DROMEQ8SR99, TRM1_ENCCU
B9LSI7, TRM1_HALLTQ5UYV8, TRM1_HALMAB0R713, TRM1_HALS3
P57705, TRM1_HALSAQ18EA0, TRM1_HALWDQ9NXH9, TRM1_HUMAN
A6UUN6, TRM1_META3Q8TGX6, TRM1_METACA7I9E9, TRM1_METB6
Q466T6, TRM1_METBFQ12Y46, TRM1_METBUQ2FN43, TRM1_METHJ
Q58356, TRM1_METJAQ8TYY7, TRM1_METKAA2SRK9, TRM1_METLZ
A4FZY5, TRM1_METM5A9A871, TRM1_METM6A6VIL5, TRM1_METM7
Q8PU28, TRM1_METMAP0CW64, TRM1_METMIA3CW75, TRM1_METMJ
P0CW65, TRM1_METMPB8GF12, TRM1_METPEA5UM08, TRM1_METS3
A4YHH9, TRM1_METS5Q2NI56, TRM1_METSTO27258, TRM1_METTH
Q3TX08, TRM1_MOUSEQ3IUJ2, TRM1_NATPDQ9V1P3, TRM1_PYRAB
Q8ZWT5, TRM1_PYRAEA4WMB7, TRM1_PYRARA3MTQ5, TRM1_PYRCJ
P81554, TRM1_PYRFUO59493, TRM1_PYRHOA1RV26, TRM1_PYRIL
B1YCV9, TRM1_PYRNVP20300, TRM1_PYRWOC3NHQ8, TRM1_SACI1
C3MPR5, TRM1_SACI2C3N5E1, TRM1_SACI3C3MYQ9, TRM1_SACI4
C4KH07, TRM1_SACI6C3NDZ5, TRM1_SACI7Q97ZH0, TRM1_SACS2
Q9P804, TRM1_SCHPOQ4J947, TRM1_SULACQ971V9, TRM1_SULTO
P57706, TRM1_THEACC5A6N2, TRM1_THEGJQ5JIB3, TRM1_THEKO
B6YUU9, TRM1_THEONQ97AR2, TRM1_THEVOP15565, TRM1_YEAST
Q9SRU7, TRM2_ARATH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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