Expasy logo

ENZYME

ENZYME entry: EC 2.1.1.218

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.218
Accepted Name
tRNA (adenine(9)-N(1))-methyltransferase
Alternative Name(s)
tRNA(m(1)G(9)/m(1)A(9))-methyltransferase
tRNA m(1)A(9)-methyltransferase
Reaction catalysed
adenosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)
Comment(s)
  • The enzyme from Sulfolobus acidocaldarius specifically methylates adenine(9) in tRNA.
  • The bifunctional enzyme from Thermococcus kodakaraensis also catalyzes the methylation of guanine(9) in tRNA (cf. EC 2.1.1.221).
  • Formerly EC 2.1.1.36.
Cross-references
BRENDA2.1.1.218
EC2PDB2.1.1.218
ExplorEnz2.1.1.218
KEGG Ligand Database for Enzyme Nomenclature2.1.1.218
IUBMB Enzyme Nomenclature2.1.1.218
MEDLINEFind literature relating to 2.1.1.218
MetaCyc2.1.1.218
Rhea expert-curated reactions2.1.1.218
UniProtKB/Swiss-Prot
Q2KI45, TM10C_BOVINQ7L0Y3, TM10C_HUMANQ3UFY8, TM10C_MOUSE
Q5U2R4, TM10C_RATA4IHS0, TM10C_XENTRQ4J894, TRM10_SULAC
Q5JD38, TRM10_THEKO

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-