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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
[Dimethylamine--corrinoid protein] Co-methyltransferase.
Alternative Name(s)
Dimethylamine methyltransferase.
Reaction catalysed
Dimethylamine + a [Co(I) dimethylamine-specific corrinoid protein] <=> a [methyl-Co(III) dimethylamine-specific corrinoid protein] + methylamine
  • The enzyme, which catalyzes the transfer of a methyl group from dimethylamine to a dimethylamine-specific corrinoid protein (MtbC), is involved in methanogenesis from dimethylamine.
  • The enzyme contains the unusual amino acid pyrrolysine.
  • Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state.
  • During methylation the cobalt is oxidized to the Co(III) state.
  • The methylated corrinoid protein is substrate for EC
PRIAM enzyme-specific profiles2.1.1.249
KEGG Ligand Database for Enzyme Nomenclature2.1.1.249
IUBMB Enzyme Nomenclature2.1.1.249
MEDLINEFind literature relating to
Q9P9M9, MTBB3_METBA;  P58972, MTBB3_METMA;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-