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ENZYME

ENZYME entry: EC 2.1.1.317

Accepted Name
sphingolipid C(9)-methyltransferase
Reaction catalysed
a (4E,8E)-4-sphinga-4,8-dienine ceramide + S-adenosyl-L-methionine <=> a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide + H(+) + S-adenosyl-L-homocysteine
Comment(s)
The enzyme, characterized from the fungi Komagataella pastoris and Fusarium graminearum, acts only on ceramides and has no activity with free sphingoid bases or glucosylceramides.
Cross-references
BRENDA2.1.1.317
EC2PDB2.1.1.317
ExplorEnz2.1.1.317
PRIAM enzyme-specific profiles2.1.1.317
KEGG Ligand Database for Enzyme Nomenclature2.1.1.317
IUBMB Enzyme Nomenclature2.1.1.317
IntEnz2.1.1.317
MEDLINEFind literature relating to 2.1.1.317
MetaCyc2.1.1.317
Rhea expert-curated reactions2.1.1.317
UniProtKB/Swiss-Prot
I1RJD6, C9MT1_GIBZEI1RNL0, C9MT2_GIBZEQ5APD4, C9MT_CANAL
C4R7Z3, C9MT_KOMPGA0A1U8QYZ5, SMTA_EMENIA0A1U8QNM5, SMTB_EMENI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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