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ENZYME entry: EC 2.1.1.339

Accepted Name
Xanthohumol 4-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + xanthohumol <=> S-adenosyl-L-homocysteine + 4-O-methylxanthohumol
Comment(s)
  • The enzyme from hops (Humulus lupulus) has a broad substrate specificity.
  • The best substrates in vitro are resveratrol, desmethylxanthohumol, chalconaringenin and isoliquiritigenin.
Cross-references
BRENDA2.1.1.339
EC2PDB2.1.1.339
ExplorEnz2.1.1.339
PRIAM enzyme-specific profiles2.1.1.339
KEGG Ligand Database for Enzyme Nomenclature2.1.1.339
IUBMB Enzyme Nomenclature2.1.1.339
IntEnz2.1.1.339
MEDLINEFind literature relating to 2.1.1.339
MetaCyc2.1.1.339
Rhea expert-curated reactions2.1.1.339
UniProtKB/Swiss-Prot
B0ZB56, OMT2_HUMLU

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