ENZYME entry: EC 2.1.1.350
| Accepted Name |
|---|
| Menaquinone C(8)-methyltransferase.
|
| Reaction catalysed |
|---|
- 2 S-adenosyl-L-methionine + a menaquinone + reduced flavodoxin <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + an 8-methylmenaquinone + oxidized flavodoxin
- 2 S-adenosyl-L-methionine + a 2-demethylmenaquinone + reduced flavodoxin <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + a 2-demethyl-8-methylmenaquinone + oxidized flavodoxin
|
| Comment(s) |
|---|
| The enzyme, found in a wide range of bacteria and archaea, is a
radical SAM (AdoMet) enzyme that utilizes two molecules of
S-adenosyl-L-methionine, one as the methyl group donor, and one for
the creation of a 5'-deoxyadenosine radical that drives the reaction
forward.
|
| Cross-references |
|---|
| BRENDA | 2.1.1.350 |
| EC2PDB | 2.1.1.350 |
| ExplorEnz | 2.1.1.350 |
| PRIAM enzyme-specific profiles | 2.1.1.350 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.350 |
| IUBMB Enzyme Nomenclature | 2.1.1.350 |
| IntEnz | 2.1.1.350 |
| MEDLINE | Find literature relating to 2.1.1.350 |
| MetaCyc | 2.1.1.350 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-