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ENZYME

ENZYME entry: EC 2.1.1.n11

Accepted Name
methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase
Reaction catalysed
(2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-[protein] <=> 2'-deoxyribonucleotide-DNA + H(+) + S-methyl-L-cysteinyl-[protein]
Comment(s)
  • This protein is involved in the repair of Sp diastereomers of DNA methylphosphotriester lesions.
  • This enzyme catalyzes only one turnover and therefore is not strictly catalytic.
  • The enzyme from the bacterium Escherichia coli also has the activity of EC 2.1.1.63 while the enzyme from Bacillus subtilis does not.
Cross-references
UniProtKB/Swiss-Prot
P19219, ADAA_BACSUP06134, ADA_ECOLIP9WJW2, ALKA_MYCTO
P9WJW3, ALKA_MYCTU

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