ENZYME entry: EC 2.1.1.n11

Accepted Name

Methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase.

Reaction catalysed

DNA (containing Sp-methylphosphotriester) + protein L-cysteine <=> DNA (without Sp-methylphosphotriester) + protein S-methyl-L-cysteine

Cofactor(s)

Zn(2+).

Comment(s)

This protein is involved in the repair of Sp diastereomers of DNA methylphosphotriester lesions.
This enzyme catalyzes only one turnover and therefore is not strictly catalytic.
The enzyme from the bacterium Escherichia coli also has the activity of EC 2.1.1.63 while the enzyme from Bacillus subtilis does not.

Cross-references

UniProtKB/Swiss-Prot

P19219, ADAA_BACSU;	P06134, ADA_ECOLI;	P9WJW2, ALKA_MYCTO;
P9WJW3, ALKA_MYCTU;

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.

All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-