ENZYME entry: EC 2.3.1.156
Accepted Name |
Phloroisovalerophenone synthase.
|
Alternative Name(s) |
3-methyl-1-(trihydroxyphenyl)butan-1-one synthase. |
Valerophenone synthase. |
Reaction catalysed |
Isovaleryl-CoA + 3 malonyl-CoA <=> 4 CoA + 3 CO(2) + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one |
Comment(s) |
- Closely related to EC 2.3.1.74.
- The product, 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one,
is phloroisovalerophenone.
- Also acts on isobutyryl-CoA as substrate to give
phlorisobutyrophenone.
- The products are intermediates in the biosynthesis of the bitter
(alpha) acids in hops (Humulus lupulus).
|
Cross-references |
PROSITE | PDOC00403 |
BRENDA | 2.3.1.156 |
EC2PDB | 2.3.1.156 |
ExplorEnz | 2.3.1.156 |
PRIAM enzyme-specific profiles | 2.3.1.156 |
KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.156 |
IUBMB Enzyme Nomenclature | 2.3.1.156 |
IntEnz | 2.3.1.156 |
MEDLINE | Find literature relating to 2.3.1.156 |
MetaCyc | 2.3.1.156 |
UniProtKB/Swiss-Prot |
|
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