ENZYME entry: EC 2.3.1.179
Accepted Name |
Beta-ketoacyl-[acyl-carrier-protein] synthase II.
|
Alternative Name(s) |
3-oxoacyl-acyl carrier protein synthase I. |
Beta-ketoacyl-ACP synthase II. |
KAS II. |
KASII. |
Reaction catalysed |
A (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] <=> a (Z)-3-oxooctadec-11-enoyl-[acyl-carrier protein] + CO(2) + an [acyl-carrier protein] |
Comment(s) |
- Involved in the dissociated (or type II) fatty acid biosynthesis
system that occurs in plants and bacteria.
- While the substrate specificity of this enzyme is very similar to
that of EC 2.3.1.41, it differs in that palmitoleoyl-ACP is not a
good substrate of EC 2.3.1.41 but is an excellent substrate of this
enzyme.
- The fatty-acid composition of Escherichia coli changes as a function
of growth temperature, with the proportion of unsaturated fatty acids
increasing with lower growth temperature.
- Controls the temperature-dependent regulation of fatty-acid
composition, with mutants lacking this acivity being deficient in the
elongation of palmitoleate to cis-vaccenate at low temperatures.
|
Cross-references |
PROSITE | PDOC00529 |
BRENDA | 2.3.1.179 |
EC2PDB | 2.3.1.179 |
ExplorEnz | 2.3.1.179 |
PRIAM enzyme-specific profiles | 2.3.1.179 |
KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.179 |
IUBMB Enzyme Nomenclature | 2.3.1.179 |
IntEnz | 2.3.1.179 |
MEDLINE | Find literature relating to 2.3.1.179 |
MetaCyc | 2.3.1.179 |
Rhea expert-curated reactions | 2.3.1.179 |
UniProtKB/Swiss-Prot |
O34340, FABF_BACSU; | Q83E37, FABF_COXBU; | P0AAI7, FABF_ECO57; |
P0AAI6, FABF_ECOL6; | P0AAI5, FABF_ECOLI; | P56902, FABF_RHIME; |
P0AAI8, FABF_SHIFL; | Q5HHA1, FABF_STAAC; | Q99VA6, FABF_STAAM; |
Q7A6F8, FABF_STAAN; | Q6GIA3, FABF_STAAR; | Q6GAU2, FABF_STAAS; |
Q5TKS0, FABF_STAAU; | Q8NXE1, FABF_STAAW; | P73283, FABF_SYNY3; |
Q9KQH9, FABF_VIBCH; | P55338, FABF_VIBHA; |
|
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