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ENZYME entry: EC 2.3.1.208

Accepted Name
4-hydroxycoumarin synthase.
Reaction catalysed
2-hydroxybenzoyl-CoA + malonyl-CoA <=> 4-hydroxycoumarin + CO2 + 2 CoA
Comment(s)
The enzyme, a polyketide synthase, can also accept benzoyl-CoA as substrate, which it condenses with 3 malonyl-CoA molecules to form 3,5-dihydroxybiphenyl (cf. EC 2.3.1.177).
Cross-references
BRENDA2.3.1.208
EC2PDB2.3.1.208
ExplorEnz2.3.1.208
PRIAM enzyme-specific profiles2.3.1.208
KEGG Ligand Database for Enzyme Nomenclature2.3.1.208
IUBMB Enzyme Nomenclature2.3.1.208
IntEnz2.3.1.208
MEDLINEFind literature relating to 2.3.1.208
MetaCyc2.3.1.208
Rhea expert-curated reactions2.3.1.208
UniProtKB/Swiss-Prot
D2DRC4, BIPS2_SORAU;  D2DRC5, BIPS3_SORAU;  

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