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ENZYME

ENZYME entry: EC 2.3.1.226

Accepted Name
carboxymethylproline synthase
Reaction catalysed
(S)-1-pyrroline-5-carboxylate + H(+) + H2O + malonyl-CoA <=> (2S,5S)-5-carboxymethylproline + CO2 + CoA
Comment(s)
The enzyme is involved in the biosynthesis of the carbapenem beta- lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum.
Cross-references
BRENDA2.3.1.226
EC2PDB2.3.1.226
ExplorEnz2.3.1.226
PRIAM enzyme-specific profiles2.3.1.226
KEGG Ligand Database for Enzyme Nomenclature2.3.1.226
IUBMB Enzyme Nomenclature2.3.1.226
IntEnz2.3.1.226
MEDLINEFind literature relating to 2.3.1.226
MetaCyc2.3.1.226
Rhea expert-curated reactions2.3.1.226
UniProtKB/Swiss-Prot
Q9XB60, CARB_PECCC

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